Extension Study to Evaluate the Long-Term Safety and Durability of Effect of LUM001 in the Treatment of Cholestatic Liver Disease in Pediatric Subjects with Alagille Syndrome

The IMAGINE-II study was a multicenter, extension study of LUM001 in children diagnosed with Alagille syndrome (ALGS) who had completed participation in a core LUM001 treatment protocol (ITCH study). Efficacy was assessed by evaluating the effect of LUM001 on the biochemical markers and pruritus associated with ALGS.

Note: If requesting access to IMAGINE-II data, it is recommended to also request access to the ITCH Study data (https://repository.niddk.nih.gov/studies/itch/) as IMAGINE-II is an extension study of ITCH.