Nsp3:nsp4 binds to nsp6

This COVID-19 event has been created by a combination of computational inference (see https://reactome.org/documentation/inferred-events) from SARS-CoV-1 data and manual curation, as described in the summation for the overall SARS-CoV-2 infection pathway.<br><br>The SARS-CoV nsp3 was shown to bind ORF7a and Nsp6 by using proteomics analysis (Neuman et al, 2008)

此次COVID-19事件系通过结合计算推理（参见https://reactome.org/documentation/inferred-events）从SARS-CoV-1数据中得出，并辅以人工编纂，具体编纂过程详述于SARS-CoV-2感染途径的整体概述中。<br><br>经蛋白质组学分析（Neuman等人，2008年）证实，SARS-CoV的nsp3蛋白能够与ORF7a和Nsp6蛋白结合。