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HIV-1 Integrase Catalytic Core Domain and C-Terminal Domain in Complex with Allosteric Integrase Inhibitor STP0404 (Pirmitegravir)

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Protein Data Bank Japan2024-02-07 更新2026-04-19 收录
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https://pdbj.org/mine/summary/8a1q
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资源简介:
HIV-1 Integrase Catalytic Core Domain and C-Terminal Domain in Complex with Allosteric Integrase Inhibitor STP0404 (Pirmitegravir) Descriptor: (2S)-tert-butoxy{4-(4-chlorophenyl)-2,3,6-trimethyl-1-[(1-methyl-1H-pyrazol-4-yl)methyl]-1H-pyrrolo[2,3-b]pyridin-5-yl}acetic acid, 1,2-ETHANEDIOL, Integrase, ... Authors: Singer, M.R, Pye, V.E, Cook, N.J, Cherepanov, P. Deposit date: 2022-06-01 Release date: 2023-02-01 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.06 Å) Cite: The Drug-Induced Interface That Drives HIV-1 Integrase Hypermultimerization and Loss of Function. Mbio, 14, 2023
创建时间:
2022-06-01
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