A kinetics-based model of hematopoiesis reveals extrinsic regulation of skewed lineage output from stem cells - data repository

Single-cell RNA sequencing data from five single-HSC-derived murine hematopoietic systems, as well as two polyclonal controls. The resulting clonally-resolved hematopoietic bone marrow atlas (scBM_atlas.rds) consists of 76,863 high-quality cells and covers all major hematopoietic cell types, including differentiation tracks (slingshot.rds) from the most immature HSCs to all lineage-committed progenitors (HSPCs.rds) and their continued maturation into blood and immune cells.