Analysis of association of PTPN22 ‘haplotype 5’ (rs3789607: T>C) with rheumatoid arthritis.
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https://figshare.com/articles/dataset/Analysis_of_association_of_i_PTPN22_i_haplotype_5_i_rs3789607_i_T_gt_C_with_rheumatoid_arthritis_/493289
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1 Cases top line, controls bottom line. The Carlton Set 2 cases and controls, the combined other cases and total cases deviated mildly from HWE (P = 0.02, 0.03, 0.05 and 0.02, respectively).2 Allele 2; number of chromosomes (frequency).3 Genotype data from rs17274634 were used (r2 = 1 with rs3789607 in CEPH CEU (www.hapmap.org)).4 The Mantel-Haenszel pooled OR = 0.87 [0.82–0.93], P = 7.5×10−6; Breslow-Day test for heterogeneity P = 0.083. The Mantel-Haenszel pooled OR excluding Carlton et al data was 0.91 [0.85–0.98], P = 0.016; Breslow-Day P = 0.50.
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2013-02-20
