Discovery of a potent and isoform-selective targeted covalent inhibitor of the lipid kinase PI3Kalpha
收藏Protein Data Bank Japan2024-10-23 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/3zim
下载链接
链接失效反馈官方服务：
资源简介：
Discovery of a potent and isoform-selective targeted covalent inhibitor of the lipid kinase PI3Kalpha Descriptor: 1-[4-[[2-(1H-indazol-4-yl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-yl]methyl]piperazin-1-yl]-6-methyl-hept-5-ene-1,4- dione, PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT ALPHA ISOFORM Authors: Nacht, M, Qiao, L, Sheets, M.P, Martin, T.S, Labenski, M, Mazdiyasni, H, Karp, R, Zhu, Z, Chaturvedi, P, Bhavsar, D, Niu, D, Westlin, W, Petter, R.C, Medikonda, A.P, Jestel, A, Blaesse, M, Singh, J. Deposit date: 2013-01-09 Release date: 2013-02-13 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Discovery of a Potent and Isoform-Selective Targeted Covalent Inhibitor of the Lipid Kinase Pi3Kalpha J.Med.Chem., 56, 2013
创建时间：
2013-01-09
