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Crystal structure of a benzthiophene lead bound to MAPKAP Kinase-2 (MK-2)

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Protein Data Bank Japan2023-09-06 更新2026-03-21 收录
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Crystal structure of a benzthiophene lead bound to MAPKAP Kinase-2 (MK-2) Descriptor: (3R)-3-(aminomethyl)-9-methoxy-1,2,3,4-tetrahydro-5H-[1]benzothieno[3,2-e][1,4]diazepin-5-one, MAP kinase-activated protein kinase 2 Authors: Kurumbail, R.G, Caspers, N. Deposit date: 2009-01-22 Release date: 2009-04-07 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Benzothiophene inhibitors of MK2. Part 2: improvements in kinase selectivity and cell potency. Bioorg.Med.Chem.Lett., 19, 2009
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2009-01-22
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