Dendritic cell (DC) specification and differentiation are controlled by a circuit of transcription factors, which regulate the expression of DC effector genes as well as the transcription factors them

NIAID Data Ecosystem50

Data Sheet 2_Ziyuglycoside II ameliorates chemotherapy-induced neutropenia by promoting neutrophil differentiation and functional recovery via SPI1 and C/EBPϵ transcriptional regulation.xlsx

细胞分化调控

化疗中性粒细胞减少症

BackgroundChemotherapy-induced neutropenia (CIN) remains a major dose-limiting toxicity associated with myelosuppressive chemotherapy regimens. The development of therapeutic strategies capable of eff

NIAID Data Ecosystem00

Microfluidic Perfusion for Regulating Diffusible Signaling in Stem Cells

细胞分化调控

微流控细胞培养

BackgroundAutocrine & paracrine signaling are widespread both in vivo and in vitro, and are particularly important in embryonic stem cell (ESC) pluripotency and lineage commitment. Although autocrine

NIAID Data Ecosystem50

Transcriptome analysis of RUNX3-primed embryonic stem cell derived dendritic cells (ES-DCs)

细胞分化调控

RUNX2基因功能

We examined the effects of Runx3 induction in murine embryonic stem cell derived dendritic cells (ES-DCs) using a doxycycline-inducible transgenic cell line. We used one set of control samples without

NIAID Data Ecosystem10

Dynamic alterations of 3D chromatin structure during differentiation

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