microRNA expression profiling of the response of the dorsal motor nucleus of the vagus to physiological perturbations and cardiac injury

We developed microRNA expression profiling data from the dorsal motor nucleus of the vagus (DMV) neurons under homeostasis and following physiological perturbations of remote ischemic preconditioning and cardiac ischemia. Male Sprague-Dawley rats were subjected to remote ischemia preconditioning (rIPC), ligation of the left anterior descending artery (LAD), or rIPC with LAD following two hours later (rIPC 2h/LAD). All samples were collected 24 hours after LAD.本研究构建了稳态下以及经远程缺血预处理（remote ischemic preconditioning，rIPC）、心脏缺血两种生理扰动后的迷走神经背运动核（dorsal motor nucleus of the vagus，DMV）神经元的微小RNA（microRNA）表达谱数据。实验采用雄性斯普拉-道来（Sprague-Dawley）大鼠，将其分别施以三种处理方案：仅远程缺血预处理组、仅左前降支动脉（left anterior descending artery，LAD）结扎组，以及先接受rIPC、2小时后再实施LAD结扎的rIPC 2h/LAD联合处理组。所有样本均采集于LAD结扎后24小时。