Structure of PKA phosphorylated human RyR2-R420Q in the closed state in the presence of ARM210

Structure of PKA phosphorylated human RyR2-R420Q in the closed state in the presence of ARM210 Descriptor: 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... Authors: Miotto, M.C, Marks, A.R. Deposit date: 2023-11-09 Release date: 2023-11-22 Last modified: 2024-10-30 Method: ELECTRON MICROSCOPY (3.53 Å) Cite: Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders. Nat Commun, 15, 2024