Crystal structure of human AKR1B1 complexed with NADP+ and compound 37
收藏Protein Data Bank Japan2024-01-17 更新2026-03-21 收录
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Crystal structure of human AKR1B1 complexed with NADP+ and compound 37 Descriptor: 2-[5-(4-chlorophenyl)-3-methyl-1-oxidanylidene-pyrimido[4,5-c]quinolin-2-yl]ethanoic acid, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Cousido-Siah, A, Ruiz, F.X, Mitschler, A, Metwally, K, Podjarny, A. Deposit date: 2017-08-23 Release date: 2018-05-09 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (0.94 Å) Cite: Design, synthesis, structure-activity relationships and X-ray structural studies of novel 1-oxopyrimido[4,5-c]quinoline-2-acetic acid derivatives as selective and potent inhibitors of human aldose reductase. Eur J Med Chem, 152, 2018
创建时间：
2017-08-23
