Whole lung transcriptome from lung epithelial IRE1α knockout mice
收藏NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE190822
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This experiment sought to characterize the whole lung transcriptional changes induced by loss of IRE1a function in the lung epithelium. Mice were Shh(Cre/+) IRE1a(fl/fl) on the C57BL/6 background, and had loss of IRE1a function in the epithelium based on XBP1 splicing activity. Lungs from uninjured mice were harvested, flash-frozen, homogenized, and RNA isolated by Trizol extraction. Principal treatment groups are: IRE1α epithelial knockout (Shh Cre/+ IRE1α fl/fl, 5 mice) and IRE1α flox (Shh +/+ IRE1α fl/fl, 5 mice).
创建时间:
2022-03-03



