Crystal structure of CDK2/cyclin E in complex with PF-06873600
收藏Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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Crystal structure of CDK2/cyclin E in complex with PF-06873600 Descriptor: 6-(difluoromethyl)-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]-2-{[1-(methylsulfonyl)piperidin-4-yl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one, Cyclin-dependent kinase 2, G1/S-specific cyclin-E1 Authors: McTigue, M.A, He, Y, Ferre, R.A. Deposit date: 2020-10-26 Release date: 2021-06-23 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.187 Å) Cite: Discovery of PF-06873600, a CDK2/4/6 Inhibitor for the Treatment of Cancer. J.Med.Chem., 64, 2021
创建时间：
2020-10-26
