Supporting data and analysis code for immune cell-specific gene expression and pancreatic cancer susceptibility assessed by Mendelian randomization and colocalization
收藏资源简介:
This record contains the author-generated summary-level results and analysis code supporting the manuscript “Immune cell-specific gene expression and pancreatic cancer susceptibility assessed by Mendelian randomization and colocalization.” Contents include the complete MR result screen, cross-outcome comparisons, diagnostic and uncertainty analyses, regional colocalization outputs with prior sensitivity, same-donor native-effect sensitivity, external BLUEPRINT/DICE/BioBank Japan validation outputs, numbered R scripts, source locators and fingerprints, software-version records, and bounded reproduction checks. No participant-level data, personal identifiers, credentials, full upstream GWAS/eQTL files, LD genotypes, or executables are included. Upstream data remain with OneK1K, FinnGen, the GWAS Catalog, eQTL Catalogue, DICE, BioBank Japan, and 1000 Genomes under their respective terms. No association survived whole-screen correction, no colocalization result met the prespecified robust strong-support criterion, and no candidate achieved fully independent exposure-plus-outcome replication. The deposited findings are hypothesis-generating and do not establish causal genes or validated therapeutic targets.



