遇见数据集

Supporting data and analysis code for immune cell-specific gene expression and pancreatic cancer susceptibility assessed by Mendelian randomization and colocalization

收藏
Zenodo2026-09-25 更新2026-10-01 收录
官方服务:

资源简介:

This record contains the author-generated summary-level results and analysis code supporting the manuscript “Immune cell-specific gene expression and pancreatic cancer susceptibility assessed by Mendelian randomization and colocalization.” Contents include the complete MR result screen, cross-outcome comparisons, diagnostic and uncertainty analyses, regional colocalization outputs with prior sensitivity, same-donor native-effect sensitivity, external BLUEPRINT/DICE/BioBank Japan validation outputs, numbered R scripts, source locators and fingerprints, software-version records, and bounded reproduction checks. No participant-level data, personal identifiers, credentials, full upstream GWAS/eQTL files, LD genotypes, or executables are included. Upstream data remain with OneK1K, FinnGen, the GWAS Catalog, eQTL Catalogue, DICE, BioBank Japan, and 1000 Genomes under their respective terms. No association survived whole-screen correction, no colocalization result met the prespecified robust strong-support criterion, and no candidate achieved fully independent exposure-plus-outcome replication. The deposited findings are hypothesis-generating and do not establish causal genes or validated therapeutic targets.

提供机构:
Zenodo
创建时间:
2026-09-25
二维码
社区交流群
二维码
科研交流群
商业服务