Data: Gene expression of Mowat-Wilson syndrome patient derived GABAergic interneurons
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https://figshare.scilifelab.se/articles/dataset/Data_Gene_expression_of_Mowat-Wilson_syndrome_patient_derived_GABAergic_interneurons/20472144/1
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资源简介：
IPSC lines established from fibroblasts of both sibling (MW1=26, MW2=27) and two healthy donors (Ctl2=K02 and Ctl8=K08).
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Neurocortical differentiation of iPSCs (samples IPS) was carried out as described using Dual-SMAD inhibition that promotes conversion into neural stem cells (NSC) for 10 days (samples INT) followed by directed differentiation into cortical lineages for 65 days (samples D65).
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Bulk RNA sequencing reads were aligned to the ENSEMBL human reference genome (Homo_sapiens.GRCh37.75) and gene counts were generated using the STAR read aligner. The count data is not normalized and can be used with DESEq2.
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Expression data was generated for all three time points IPS -> INT (D10) -> D65
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File names are:
timepoint_SampleReadsPerGene.out.tab
提供机构：
Uppsala University
创建时间：
2022-08-12
