Sier2017_estrogen_PBPK_GSMN
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下载链接：
https://www.omicsdi.org/dataset/biomodels/MODEL1711210003
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资源简介：
Physiologically-based Pharmacokinetic (PBPK) model of estradiol disposition in humans.
Based on Sier et al_2017_estrogen PBPK_simple (MODEL1711210001), but with intrinsic (i.e. liver-mediated) clearance term replaced by a genome scale metabolic network. Extrahepatic clearance is still represented by as simple mass action
Model was developed in the Multi-Formalism Interaction Network Simulator (MuFINS), as described in Wu et al 2017 (doi: 10.1038/npjsba.2016.32). relevant Software and tutorials can be found at http://sysbio3.fhms.surrey.ac.uk/mufins/
创建时间：
2018-02-02
