Dehydrative Transformation of Spirooxindoles to Pyrido[2,3‑b]indoles via POCl3
收藏Figshare2019-03-20 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Dehydrative_Transformation_of_Spirooxindoles_to_Pyrido_2_3_i_b_i_indoles_via_POCl_sub_3_sub_/7869023
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资源简介：
A two-step one-pot efficient synthesis of pyrido[2,3-b]indoles via reaction between isatin, α-amino acid, and dipolarophile has been developed. The initial 1,3-dipolar cycloaddition between the reactants that is performed in the presence of either CuI or methanol results in spirooxindoles that undergo POCl3-mediated intramolecular dehydrative transformation to afford the title compounds.
创建时间：
2019-03-20
