Lysine deacetylases (KDACs or HDACs) biological effects assessed by fixed cell fluorescence microscopy in HT1080 cells

These data have been utilized in the following publications: ---- (1) Bornes KE, Moody MA, Huckaba TM, Benz MC, McConnell EC, Foroozesh M, Barnes VH, Collins-Burow BM, Burow ME, Watt TJ, Toro TB. Lysine deacetylase inhibitors have low selectivity in cells and exhibit predominantly off-target effects. FEBS Open Bio 2025, 15, 94-107. https://doi.org/10.1002/2211-5463.13896 ---- (2) Toro TB, Hammad RH, Huckaba TM, Watt TJ. Loss of cohesin deacetylation through KDAC8 inactivation leads to chromosomal instability driven by reduced cohesin complex turnover. Under review. ---- (3) Joseph TV, Pham AB, Bornes KE, Hammad RH, Rousseve-Ross CA, Huckaba TM, Watt TJ, Toro TB. KDAC6 influences cell morphology and motility through positive and negative regulation of F-actin remodeling. Under review.