We recently described a humanised conditional knock-in mouse model of the main form of NPM1c1. In this model, activation of Npm1c mutations in haemopoietic stem cells (HSC) by Mx1-Cre caused, amongst
Using Sleeping Beauty mutagenesis in the mouse we have performed a screen to identify mechanisms of resistance to FGF inhibitors. In this experiment we pulldown transposon insertion sites with the aim
