Figure S1 - Cross-Talk between TLR4 and FcγReceptorIII (CD16) Pathways

Cytokine response of PMNs and macrophages to Zymosan and Pam3Cys. In vitro cytokine responses to non-TLR4 agonists of elicited peritoneal phagocytes from Wt or TLR4 mut mice. PMNs (A–D) and macrophages (E–H) (3×106 cells/ml) were incubated (for 4 hr) with serum-opsonized zymosan particles (300 µg/ml) or Pam3Cys (1 µg/ml). Ctrl = control levels of non-stimulated cells. For each condition n≥3. Differences between controls and stimulated cells were found to be statistically significant (p<0.05). (0.50 MB EPS)