Multi-omic investigations of mouse liver subjected to simulated spaceflight freezing and storage protocols
收藏DataCite Commons2026-02-19 更新2025-04-16 收录
下载链接：
https://osdr.nasa.gov/bio/repo/data/studies/OSD-49
下载链接
链接失效反馈官方服务：
资源简介：
This study compares standard laboratory protocols for tissue freezing and storage with a simulation of the delayed processing of liver specimens and long-term storage protocols used during the Rodent Research-1 (RR-1) payload. Liver samples from twelve-week old female C57BL/6J mice (snap frozen vs. 25 min. slow-frozen and stored for 3 days vs. 1 year) received from the RR-1 project were processed for extraction of RNA, DNA and protein. RNA-seq, whole genome bisulfite sequencing and mass spectrometry proteomics were performed. These multi-omics datasets will help distinguish the effects of freezing and storage time that could confound the interpretation of the Rodent Research-1 datasets.
提供机构：
NASA GeneLab
创建时间：
2020-06-29
