Peroxisomes are signaling patforms for antiviral innate immunity
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Peroxisomes are signaling patforms for antiviral innate immunity
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2010-11-04
相关数据集
DataSheet_1_Negative Regulation of RNF90 on RNA Virus-Triggered Antiviral Immune Responses Targeting MAVS.docx
The antiviral innate immunity is the first line of host defense against viral infection. Mitochondrial antiviral signaling protein (MAVS, also named Cardif/IPS-1/VISA) is a critical protein in RNA vir
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RNF34 functions in immunity and selective mitophagy by targeting MAVS for autophagic degradation
Viral infection triggers the formation of mitochondrial antiviral signaling protein (MAVS) aggregates, which potently promote immune signaling. Autophagy plays an important role in controlling MAVS-me
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AXIN1 boosts antiviral response through IRF3 stabilization and induced phase separation
Axis inhibition protein 1 (AXIN), a scaffold protein interacting with various critical molecules, plays a vital role in determining cell fate. However, its impact on the antiviral innate immune resp
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Rapid induction of antiviral ISG mRNAs following RdRP expression in human lung epithelial cells.
(A) DOX-inducible RdRP A549 cell lines were generated using lentiviral vectors that inducibly co-express RdRP or RdRPΔcat and resistance to puromycin. Vector terminology: Tsin-TetON-RdRP-IRESpuro (Tet
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Table_2_Initial activation of STAT2 induced by IAV infection is critical for innate antiviral immunity.pdf
STAT2 is an important transcription factor activated by interferons (IFNs) upon viral infection and plays a key role in antiviral responses. Interestingly, here we found that phosphorylation of STAT2
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