Comparison of Mcm5 and NMP22 test performance across grade and stage.

Abbreviations: CI, 95% confidence interval; IQR, interquartile range; med, median; FNR, false negative rate.aMann-Whitney test (for Test value) or Chi-squared test (for FNR), comparison with Normal group.bMann-Whitney test (for Test value) or Chi-squared test (for FNR), comparison with previous, i.e. Grade 2 vs Grade 1, Grade 3 vs Grade 2.cJonckheere-Terpstra test for trend (for Test value) or Chi-squared test for linear by linear association, across Grade or Stage, excluding Normal group.dData analysis using 2150-cell cut-point for Mcm5 test.eExcludes 8 CIS and 1 adenocarcinoma from 210 UCC cases having an MCM5 test value.fData analysis using 10 U/mL cut-point for NMP22 test.gExcludes 7 CIS from the 195 UCC cases having an NMP22 test value.