Data from QIN-BREAST-02

This data is from a multi-site, multi-parametric quantitative MRI study of adult (18+ years old) females diagnosed with invasive breast cancer. Subjects all had a lesion size >1cm in longest dimension and were undergoing neoadjuvant therapy. Participants were scanned prior to any therapy and then 2-3 times after the initiation of neoadjuvant therapy, depending upon their treatment regimen. All data sets were acquired with a research-only protocol, including: DWI (SE EPI), OGSE, qMT, B0 map, multi-flip T1 map, Bloch-Siegert B1 map, DCE, and a T1-weighted anatomical image. This dataset is an extension of the original QIN-Breast ( https://doi.org/10.7937/K9/TCIA.2016.21JUebH0 ) collection, with updated scan protocols and data collected at both Vanderbilt University Medical Center and the University of Chicago to demonstrate reproducible results at multiple sites (both using Philips 3T MR scanners).

本数据集源自一项针对成年（18岁及以上）女性浸润性乳腺癌患者的多中心、多参数定量磁共振成像研究。所有受试者的病灶最长径均大于1cm，且正在接受新辅助治疗。研究对象在接受任何治疗前完成首次扫描，随后根据其治疗方案，在新辅助治疗启动后再进行2至3次扫描。所有数据集均采用仅用于研究的采集协议，涵盖以下序列与图像：扩散加权成像（Diffusion Weighted Imaging, DWI，SE EPI序列）、正交梯度自旋回波（Orthogonal Gradient Spin Echo, OGSE）、定量磁化传递成像（quantitative Magnetization Transfer, qMT）、B0场图（B0 map）、多翻转角T1图（multi-flip T1 map）、Bloch-Siegert B1图、动态对比增强磁共振成像（Dynamic Contrast Enhanced, DCE）以及T1加权解剖图像。本数据集为原始QIN-Breast数据集（https://doi.org/10.7937/K9/TCIA.2016.21JUebH0）的扩展版本，更新了扫描协议，新增了范德堡大学医学中心与芝加哥大学的采集数据，两个中心均采用飞利浦3T磁共振扫描仪，旨在验证多中心场景下的研究结果可重复性。

搜集汇总

背景与挑战

背景概述

该数据集包含乳腺癌患者治疗前后的多参数MRI数据，旨在展示多中心研究的可重复性结果，并扩展了原始QIN-Breast数据集，更新了扫描协议和增加了新的数据采集点。