Crystal structure of human mdm2 with a dihydroimidazothiazole inhibitor
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Crystal structure of human mdm2 with a dihydroimidazothiazole inhibitor Descriptor: 1-{[(5R,6S)-5,6-bis(4-chlorophenyl)-6-methyl-3-(propan-2-yl)-5,6-dihydroimidazo[2,1-b][1,3]thiazol-2-yl]carbonyl}-N,N-dimethyl-L-prolinamide, E3 ubiquitin-protein ligase Mdm2 Authors: Shimizu, H, Katakura, S, Miyazaki, M, Naito, H, Sugimoto, Y, Kawato, H, Okayama, T, Soga, T. Deposit date: 2012-10-16 Release date: 2013-02-06 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Lead optimization of novel p53-MDM2 interaction inhibitors possessing dihydroimidazothiazole scaffold Bioorg.Med.Chem.Lett., 23, 2013
创建时间：
2012-10-16
