官方服务：
资源简介：
Transcriptome Analysis of Fasudil Treatment in the APP/PS1 Tg Mouse Model of Alzheimer’s Disease
应用场景：
创建时间：
2021-11-23
相关数据集
total RNA-seq from gastrocnemius (ENCSR093SMP)
5xFAD X Cast gastrocnemius_8-10 months female For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Polic
NIAID Data Ecosystem150
Identification of a shared disease-associated oligodendrocyte signature among multiple CNS pathologies
The role of oligodendrocytes in Alzheimer’s disease (AD) has never been fully elucidated. To dissect their possible contribution to the disease we perform single-cell RNA-sequencing (scRNA-seq) on the
NIAID Data Ecosystem110
RNA-Seq analysis of E4FAD mouse brain cortex to evaluate the impact of omega-6 fatty acid docosapentaenoic acid on neuroinflammation
Purpose: In this study, we report on an effective anti-inflammatory lipid, linoleic acid (LA) metabolite docosapentaenoic acid (DPAn-6) treatment of aged humanized EFAD mice with advanced AD pathology
NIAID Data Ecosystem80
Bulk and single cell sequencing (bc-Smart-seq2 and 10XGenomics) of human microglia from post mortem AD CNS tissue. Bulk and single cell sequencing (bc-Smart-seq2 and 10XGenomics) of human microglia from post mortem AD CNS tissue
Microglia are the tissue-resident macrophages of the central nervous system (CNS). Recent studies based on bulk and single-cell RNA sequencing in mice indicate high relevance of microglia with respect
NIAID Data Ecosystem140
An investigation into the effects of ATV:Trem2 on AD model mice using scRNA-seq
WT hTfR-KI mice and APP/SAA hTfR-KI mice were treated with one of: Isotype control ATV, naked 4D9 (activating Trem2 Ab), or ATV:4D9. Drugs were delivered IV. After 24 hours, mice were sacrificed, and
NIAID Data Ecosystem100
