Microarray comparing CMV-specific CD8+ T cells from liver sinusoid and peripheral blood
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE141508
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资源简介：
The liver is an immunologically unique organ in terms of the regulation of immuno-tolerance and immune responses. Recently, non-recirculating tissue-resident memory T (TRM) cells expressing CD69 were found in various peripheral organs. In humans, a large population of CD69+CD8+ memory T cells residing in liver sinusoids shows reduced cytotoxicity. However, the trascriptional characteristics of human liver CD8+ T cells are still unknown. Therefore, we performed a microarray analysis to screen the gene expression profile in liver sinusoidal CD8+ T cells using CMV-specific CD8+ T cells from human peripheral blood and liver sinusoid. We performed microarray analysis after sorting HLA-A*0201-CMVpp65495 pentamer+CD8+ T cells from paired LSMCs and PBMCs.
创建时间：
2020-03-06
