Whole genome deterministic molecular haplotyping
收藏NIAID Data Ecosystem2026-03-07 收录
下载链接：
https://www.ncbi.nlm.nih.gov/sra/SRP004673
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资源简介：
Conventional experimental methods of studying the human genome are limited by the inability to independently study each of the homologous copies of the chromosomes. These haplotypes are important features of the genome but in general cannot be easily determined. We developed a microfluidic device that is capable of separating and amplifying homologous copies of each chromosome within a single human metaphase cell. SNP array analysis of amplified materials obtained from single cells enabled us to achieve completely deterministic whole-genome personal haplotypes of four individuals.
创建时间：
2013-08-23
