Overview of Included Studies and Sample Sizes.

1 Total sample sizes by Population Group are N = 346 African American, N = 352 European American, N = 574 Han Chinese and N = 280 Hispanic.2 This count omits 100 pedigree IDs dropped prior to processing, primarily due to uninformativeness for linkage or duplication across Studies 6, 7.3 15 families were dropped (and 3 subsumed by joining) prior to this stage, see Appendix S1 & Table S1 for details.4 Families used in this paper to compare results across the four data configurations are those remaining after genotype processing with at least two schizophrenia cases according to either the HGI or CAPS clinical criteria, omitting 16 such families with bitsize larger than 24 for computational reasons.5 Study 7 included trios in the published total.