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Crystal Structure of Checkpoint Kinase 2 in complex with Inhibitor PV1531

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Protein Data Bank Japan2023-12-20 更新2026-03-21 收录
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Crystal Structure of Checkpoint Kinase 2 in complex with Inhibitor PV1531 Descriptor: (2E)-N-hydroxy-2-[1-(4-{[(4-{(1E)-1-[2-(N'-hydroxycarbamimidoyl)hydrazinylidene]ethyl}phenyl)carbamoyl]amino}phenyl)ethylidene]hydrazinecarboximidamide, MAGNESIUM ION, NITRATE ION, ... Authors: Lountos, G.T, Jobson, A.G, Tropea, J.E, Self, C.R, Pommier, Y, Shoemaker, R.H, Zhang, G, Waugh, D.S. Deposit date: 2011-03-14 Release date: 2011-11-16 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.77 Å) Cite: Structural Characterization of Inhibitor Complexes with Checkpoint Kinase 2 (Chk2), a Drug Target for Cancer Therapy. J.Struct.Biol., 176, 2011

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2011-03-14
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