Neuronal death in ASRGL1-knock down mice
收藏NIAID Data Ecosystem2026-05-01 收录
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ASRGL1 silencing triggers death of motor neurons and TDP-43 proteinopathy in mice. Adult female C57BL/6 mice received a stereotaxic injection to deliver 2 µl of viral solution (1013 AAV9 viral particles/ml) in the motor cortex. Half of the mice received particles with a construct encoding 4 scrambled shRNAs and the other half received particles with a construct encoding 4 shRNAs against ASRGL1. One month after the injection, brain sections were immunostained for NeuN and analyzed by confocal microscopy.
创建时间：
2024-04-13
