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Joint X-ray/neutron structure of HIV-1 protease triple mutant (V32I,I47V,V82I) with tetrahedral intermediate mimic KVS-1

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Protein Data Bank Japan2023-10-25 更新2026-03-21 收录
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Joint X-ray/neutron structure of HIV-1 protease triple mutant (V32I,I47V,V82I) with tetrahedral intermediate mimic KVS-1 Descriptor: HIV-1 Protease, N~2~-[(2R,5S)-5-({(2S,3S)-2-[(N-acetyl-L-threonyl)amino]-3-methylpent-4-enoyl}amino)-2-butyl-4,4-dihydroxynonanoyl]-L-glutaminyl-L-argininamide Authors: Kovalevsky, A, Das, A. Deposit date: 2019-07-16 Release date: 2020-06-10 Last modified: 2023-10-25 Method: NEUTRON DIFFRACTION (1.85 Å), X-RAY DIFFRACTION Cite: Visualizing Tetrahedral Oxyanion Bound in HIV-1 Protease Using Neutrons: Implications for the Catalytic Mechanism and Drug Design. Acs Omega, 5, 2020
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2019-07-16
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