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X-ray structure of Furin bound to BOS-318, a small molecule inhibitor

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Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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X-ray structure of Furin bound to BOS-318, a small molecule inhibitor Descriptor: (1-{[2-(3,5-dichlorophenyl)-6-{[2-(4-methylpiperazin-1-yl)pyrimidin-5-yl]oxy}pyridin-4-yl]methyl}piperidin-4-yl)acetic acid, 1,2-ETHANEDIOL, CALCIUM ION, ... Authors: Campobasso, N, Reid, R. Deposit date: 2021-01-11 Release date: 2022-01-12 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.24 Å) Cite: A highly selective, cell-permeable furin inhibitor BOS-318 rescues key features of cystic fibrosis airway disease. Cell Chem Biol, 29, 2022
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2021-01-11
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