Examples of Viruses and Viral Proteins Inhibiting Apoptosis.

Abbreviations: ADV, adenovirus; ANT, adenine nucleotide translocase; ASFV, African swine fever virus; BCV, baculovirus; Casp, caspase; CIDE-B, cell-death-inducing DFF-45-like effector B; CMV, cytomegalovirus; Δψm, mitochondrial transmembrane potential; EBNA, Epstein-Barr nuclear antigen; EBV, Epstein-Barr virus; ER, endoplasmic reticulum; FKBP38, 38-kDa FK506-binding protein FPV, fowl poxvirus; γHV-68, γ-herpesvirus 68; HAX-1, HS1-associated protein X-1; HHV-8, human herpesvirus 8; HVS, herpesvirus saimiri; KsBcl-2, Kaposi sarcoma Bcl-2; MMP, mitochondrial membrane permeabilization; MOMP, mitochondrial outer membrane permeabilization; MPT, mitochondrial permeability transition; MXV, Myxoma virus NF-kB, nuclear factor-kappa B; HPN, herpesvirus pan; HPO, herpesvirus papio; ORF, open reading frame; PBR, peripheral-type benzodiazepine receptor; PPVO, parapoxvirus ORF virus; RID, receptor internalization and degradation complex; TNFα, tumor necrosis factor α; UV, ultraviolet; VACV, vaccinia virus; vBcl-2, viral Bcl-2; VDAC, voltage-dependent anion channel; vFLIP, viral Fas-associated death domain-like interleukin 1β converting enzyme (FLICE) inhibitory protein; vIAP, viral inhibitor of apoptosis protein; vICA, viral inhibitor of caspase-8 activation; vMAP, viral mitochondrial antiapoptotic protein; vMIA, viral mitochondrial-localized inhibitor of apoptosis.