Additional file 4 of Pheromone sensing in Drosophila requires support cell-expressed Osiris 8

Additional file 4: Table S1. Analysis of Ir and Or subsystem-enriched genes. Annotations of genes enriched in the Ir (magenta) and Or (green) subsystems, as defined as those showing a >4-fold differential expression between amos and ato mutant antennae. This arbitrary cut-off captures all of the known chemosensory receptors expressed in the two subsystems. The dataset was cleaned from the original microarray data (GSE183763) by updating gene names and removing duplicate gene entries and those corresponding to transposons. Neuronal/non-neuronal expression is a qualitative assessment based upon the Fly Cell Atlas antennal dataset [29] and/or RNA FISH data for chemosensory receptors [17–19]: “1” = expressed; “0” = not expressed; empty cells indicate robust expression was not detected in either cell type (which may reflect sub-threshold expression level). Breadth of expression provides an approximate categorization of cell-type specific and ubiquitously expressed genes within each olfactory subsystem, based upon the qualitative assessment of the number of clusters in the Fly Cell Atlas antennal dataset in which a gene is detected: “1” = 1 cluster; “2” = 2-5 clusters; “3” = >5 clusters.