High-throughput single-cell RNA sequencing of tumor-infiltrating NK cells. High-throughput single-cell RNA sequencing of tumor-infiltrating NK cells

High-throughput single-cell RNA-seq of tumor-infiltrating NK cells uncovered an NK subset, exhibiting elevated expression of activation markers, cytolytic molecules, chemokines and cytokines when Hif1a was absent in NK cells. Overall design: Single cell transcrptome profiling of tumor-infiltrating NK cells from NK-Hif1a defecient mice and WT mice.