1The numbering refers to the central-four base pairs GG−1A+1A. 2The central-four nucleotides (or mutated derivatives) of the cleavage site are in bold face type. Nucleotide substitutions are underline
AA-TTTT L1 endonuclease cleavage consensus site. *This integration site cannot be unequivocally determined due to an associated 71-bp deletion and the lack of a TSD. The given integration site assumes