Phenyliodine Bis(trifluoroacetate)-Mediated Oxidative C–C Bond Formation: Synthesis of 3-Hydroxy-2-oxindoles and Spirooxindoles from Anilides
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https://figshare.com/articles/dataset/Phenyliodine_Bis_trifluoroacetate_Mediated_Oxidative_C_C_Bond_Formation_Synthesis_of_3_Hydroxy_2_oxindoles_and_Spirooxindoles_from_Anilides/2525386
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资源简介：
The reaction of phenyliodine bis(trifluoroacetate) (PIFA) with a series of anilides 1 (E = CO2Et) in CF3CH2OH was found to give 3-hydroxy-2-oxindole derivatives 2, while that with various anilides 1′ (E = CON(R4)Ar) afforded the C2-symmetric or unsymmetric spirooxindoles 3. These processes feature a metal-free oxidative C(sp2)–C(sp3) bond formation, followed by oxidative hydroxylation or spirocyclization.
创建时间：
2016-02-21
