Loss of MSH1 causes an array of phenotypes, including variegation, dwarfism, altered leaf morphology, delayed flowering, and male sterility. Mutant individuals showing strong phenotypes are often more
Spinning disk confocal time-lapse imaging of the first mitosis in a C. elegans embryo expressing GFP-CeCENP-A in which KNL-2 has been depleted by RNAi. GFP-CeCENP-A was imaged (strain OD101). Diffuse
A) Genomic region showing dPNUTS locus flanked by dribble and ninaA. Coding regions of the genes is represented by shading. dPNUTS produces two transcripts dPNUTS and dPNUTS-S. ninaA is a non-essentia
Mice with inactivation of the gene encoding the suppressor of cytokine signaling-1 (SOCS-1) die in neonatal life with an IFN-γ-dependent inflammatory disease dominated by fatty degeneration and necros