Discovery of IRAK4 Inhibitor 40
收藏Protein Data Bank Japan2026-03-04 更新2026-04-19 收录
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Discovery of IRAK4 Inhibitor 40 Descriptor: ACETATE ION, Interleukin-1 receptor-associated kinase 4, ~{N}-[6-methoxy-2-(2-methylsulfonylethyl)-1,3-dihydroindazol-5-yl]-6-(2-oxidanylpropan-2-yl)pyridine-2-carboxamide Authors: Schafer, M, Bothe, U, Schmidt, N, Gunther, J, Nubbemeyer, R, Siebeneicher, H, Ring, S, Boemer, U, Peters, M, Denner, K, Himmel, H, Sutter, A, Terebesi, I, Lange, M, Wengner, A.M, Guimond, N, Thaler, T, Platzek, J, Ewerspaecher, U, Steuber, H, Steinmeyer, A, Zollner, T.M. Deposit date: 2022-11-22 Release date: 2024-01-31 Last modified: 2026-03-04 Method: X-RAY DIFFRACTION (2.167 Å) Cite: Discovery of IRAK4 Inhibitors BAY1834845 (Zabedosertib) and BAY1830839 . J.Med.Chem., 67, 2024
创建时间：
2022-11-22
