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Plasmodium falciparum strain SB1-A6 whole genome sequencing

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP301980
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Plasmodium falciparum strain D6 was grown in the presence of 6-NH2Ac, an acridone compound thought to target the mtETC bc1, resulting in the strain SB1-A6 which was pan-resistance to anti-mitochondrial inhibitors. Genome sequencing revealed a mutation at position C276F in the dihydroorotate dehydrogenase (PF3D7_063300) coding sequence as well as an increase in copy number on Chromosome 6 (112701-132700).
创建时间:
2021-01-19
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