Divergent Stereocontrol of Acid Catalyzed Intramolecular Aldol Reactions of 2,3,7-Triketoesters: Synthesis of Highly Functionalized Cyclopentanones
收藏NIAID Data Ecosystem2026-03-07 收录
下载链接：
https://figshare.com/articles/dataset/Divergent_Stereocontrol_of_Acid_Catalyzed_Intramolecular_Aldol_Reactions_of_2_3_7_Triketoesters_Synthesis_of_Highly_Functionalized_Cyclopentanones/2503522
下载链接
链接失效反馈官方服务：
资源简介：
The intramolecular acid catalyzed aldol cyclization of 2,3,7-triketoesters formed from ζ-keto-α-diazo-β-ketoesters provides highly functionalized cyclopentanones with good diastereoselectivity in high overall yields via kinetically controlled and stereodivergent catalytic processes. Lewis acid catalysis gives high selectivity for the 1,2-anti tetrasubstituted cyclopentanones, whereas Brønsted acid catalysis produces the corresponding 1,2-syn diastereomer.
创建时间：
2016-02-20
