Summary raw EWAS (Ginevičienė et al. 2025. Exp Physiol.)_xlsx.zip

Title: A multi-omics investigation of sarcopenia and frailty: integrating genomic, epigenomic, and telomere length dataJournal: Experimental PhysiologyAuthors: Valentina Ginevičienė, Erinija Pranckevičienė, Alina Urnikytė, Laura Jurkūnaitė, Kristijona Gutauskaitė, Rūta Dadelienė, Justina Kilaitė, Ieva Eglė Jamontaitė, Asta Mastavičiūtė, Ildus I. Ahmetov, Vidmantas AleknaThis dataset represent raw methylation data supporting findings reported in the study "A multi-omics investigation of sarcopenia and frailty: integrating genomic, epigenomic, and telomere length data". The compressed file contains Excel workbook with the information sheet, sample sheet and matrix of beta values. The sample sheet contains IDAT identifiers and gender and age information together with the continuous Lean_mass_index phenotypic variable. The matrix of raw beta values has Illumina EPIC V2 probes as rows and the IDAT identifiers as columns. Both, the sample sheet and the matrix of raw beta values have been preprocessed where low quality probes and samples were removed. This raw dataset was used to infer associations between methylation status and lean mass index in the study. <br>