The intestinal microbiota is a microbial ecosystem of crucial importance to human health. Understanding how the microbiota confers resistance against enteric pathogens and how antibiotics disrupt that
Our goal was to compare the transcriptomic profile of lgr5+ high, medium and low cells (corresponding to centre, border and >3 row in crypts) between small and large intestine in mice. We observed dif
Here, we studied the long-term dynamics of gut microbiome and short-chain fatty acids (SCFAs) in isogenic mice with distinct microbiota baselines fed with the fermentable fiber inulin compared to the
All datasets and code used to generate figures in manuscript submitted for peer review: "Quantifying microsatellite mutation rates from intestinal stem cell dynamics in Msh2-deficient murine epitheliu
The goal of the project is to understand the difference between microbial dynamics in healthy and dysbiotic gut microbiomes using an integrated computational and experimental approach. To do so, we de