Systematic Study on the Microbiome of Bombyx mori on Artificial Diet

he sericulture industry is facing transformation and upgrading, but the mulberry-leaf oligophagous silkworm, which has been domesticated for a long time, has declined in growth and development and immune and disease resistance under artificial feed. In view of the fact that the intestinal microbes of the silkworm are closely related to the digestion, utilization, growth and development of host, this study has done a systematic study on the gut microbes of the silkworm by artificial feed: analyzed the influence of food source differences on the microbiota of silkworm gut in detail, constructed a Food-Gut-Feaces-Food microbial transfer model, screened the key genera of the system, evaluated the application of antibiotics in artificial feed. It laid the foundation for the research on the intestinal microbes of the silkworm reared by artificial feed, and also provided clues and technical references for other animal intestinal microbiota.