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Crip2 preserves hematopoietic stem and progenitor cell production through inhibition of Notch signals

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NIAID Data Ecosystem2026-05-10 收录
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To decipher the mechanisms underlying the cripDM phenotype, single cell RNA sequencing was performed on sorted, kdrl:mCherry+ cells at 30 hpf. The analysis revealed an upregulation of genes essential for vascular development. Overall design: 10X single-cell RNA sequencing from sorted mCherry+ endothelial cells from whole zebrafish embryos at 30 hours post fertilization comparing wild-type and crip mutant samples.

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2026-02-07
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