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Human iPSC-derived kidney cancer organoids as a model for ALK-rearranged renal carcinoma

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NIAID Data Ecosystem2026-05-02 收录
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Human iPS cells, in which ALK is overexpressed in a doxycycline-dependent manner, were differentiated into nephrons. Following the addition of doxycycline, RNA-seq analysis was performed over time. The study analyzed the impact of ALK on kidney differentiation and the early mechanisms of carcinogenesis.

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2024-06-27
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