Regulation of HNF4α and its target genes in Zucker diabetic fatty (ZDF) rats.

Gene expression was measured by real-time qRT-PCR in 14 weeks and 9
months old ZDF rats and lean controls
(n = 10 animals, respectively) and was
determined relative to expression of cyclophilin, which served as a
housekeeping gene. Gene expression in control rats was set to 100 and
values for ZDF rats represent transcript abundance relative to control.
Non-parametric Mann-Whitney-U-Test was used to compare ZDF and control
groups. Results are considered significant at p<0.05 (gene names
and p-values in bold). Gene expression of HNF4α in the liver of
this cohort of ZDF rats has been previously reported [43].