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pI50 and IC50 values for ibuprofen, flurbiprofen and their metabolites towards the inhibition of 0.5 µM [3H]AEA hydrolysis by rat brain FAAH.

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Figshare2015-12-02 更新2026-04-29 收录
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https://figshare.com/articles/dataset/_pI_50_and_IC_50_values_for_ibuprofen_flurbiprofen_and_their_metabolites_towards_the_inhibition_of_0_5_181_M_3_H_AEA_hydrolysis_by_rat_brain_FAAH_/1118205
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Values were determined using the log(inhibitor) vs. response – variable slope (four parameters) algorithm in the Prism 6 computer programe, with top and bottom values constrained to 100% and 0%, respectively. In all cases, Akaike’s informative criteria indicated that the curves were better fitted to these constraints than the equivalent algorithm where the bottom value was not constrained.
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2015-12-02
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