Crystal Structure of Human Liver Carboxylesterase in complex with cleavage products of Mevastatin
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Crystal Structure of Human Liver Carboxylesterase in complex with cleavage products of Mevastatin Descriptor: (1S,7S,8S,8AR)-1,2,3,7,8,8A-HEXAHYDRO-7-METHYL-8-[2-[(2R,4R)-TETRAHYDRO-4-HY DROXY-6-OXO-2H-PYRAN-2-YL]ETHYL]-1-NAPHTHALENOL, 2-METHYLBUTANOIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Fleming, C.D, Bencharit, S, Edwards, C.C, Hyatt, J.L, Morton, C.L, Howard-Williams, E.L, Potter, P.M, Redinbo, M.R. Deposit date: 2004-12-17 Release date: 2005-08-02 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil. J.Mol.Biol., 352, 2005
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2004-12-17
